Description

3-Chloro-2,4,5,6-Tetrafluorobenzotrifluoride is a highly fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its value lies in its unique structure, which combines a reactive chlorine substituent with a perfluorinated aromatic ring and a trifluoromethyl group, making it a versatile intermediate for introducing fluorinated aromatic moieties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, where it is used to create compounds with enhanced stability, bioavailability, and specific electronic properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic systems that can improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorinated aromatic core can enhance biological activity and environmental persistence.
• Liquid Crystal & Electronic Materials: Acts as a building block for fluorinated components in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), contributing to desired dielectric and optical properties.
• Polymer & Resin Modification: Employed to synthesize fluorinated monomers or additives that impart chemical resistance, low surface energy, and thermal stability to high-performance polymers and coatings.
• Organic Synthesis & Catalysis: Functions as a versatile substrate in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution, enabling the construction of complex, fluorinated molecular architectures.
• Research & Development: A valuable reagent for academic and industrial R&D focused on fluorochemistry, material science, and medicinal chemistry exploration.

Basic Information

Product Name	3-Chloro-2,4,5,6-Tetrafluorobenzotrifluoride
CAS No.	4284-09-7
Molecular Formula	C7ClF7
Molecular Weight	264.52 g/mol
Synonyms	1-Chloro-2,3,5,6-tetrafluoro-4-(trifluoromethyl)benzene; 3-Chlorotetrafluorobenzotrifluoride; Benzene, 1-chloro-2,3,5,6-tetrafluoro-4-(trifluoromethyl)-; 2,3,5,6-Tetrafluoro-3-chlorobenzotrifluoride; 4-Trifluoromethyl-2,3,5,6-tetrafluorochlorobenzene; Perfluorinated Chlorobenzotrifluoride Derivative
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,4,5,6-Tetrafluorobenzotrifluoride is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the precise requirements of advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). This compound may be sensitive to strong bases and fluorides; keep away from incompatible materials. Keep container tightly sealed when not in use to prevent moisture absorption and maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.