Description

Adrenocorticotropic Hormone, Fragment 11-24 is a synthetic peptide fragment corresponding to residues 11-24 of the full adrenocorticotropic hormone (ACTH). This specific sequence is critical for research into the structure-activity relationships of ACTH and its interaction with melanocortin receptors. It serves as a valuable biochemical tool for scientists in pharmaceutical R&D and academic institutions studying endocrine signaling, peptide hormone function, and related metabolic pathways. The compound, identified by CAS No. 4237-93-8, is supplied to meet the exacting standards of advanced life science research.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of ACTH receptor binding and activation mechanisms.
• Pharmaceutical Development: Serves as a key intermediate or pharmacophore model in the design and screening of novel therapeutics targeting melanocortin receptors.
• Endocrinology Studies: Employed in vitro and in vivo experiments to investigate the role of specific ACTH domains on adrenal cortex stimulation and steroidogenesis.
• Neuroscience Research: Applied in research exploring the effects of melanocortin peptides on the central nervous system, including potential roles in inflammation and behavior.
• Diagnostic Tool Development: Can be utilized in the development and calibration of immunoassays designed to detect or quantify ACTH or related peptides.

Basic Information

Product Name	Adrenocorticotropic Hormone, Fragment 11-24
CAS No.	4237-93-8
Molecular Formula	C₇₀H₁₀₃N₂₁O₁₉S
Molecular Weight	1655.8 g/mol
Synonyms	ACTH (11-24); Adrenocorticotropic Hormone (11-24); Corticotropin (11-24); H-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asp-Gly-Ala-Glu-Asp-Glu-NH₂; ACTH Fragment 11-24; Melanocortin Receptor Ligand Fragment; Tetracosactide fragment 11-24; Synacthen fragment 11-24
EINECS	Contact for details

Quality Control

Every batch of our Adrenocorticotropic Hormone, Fragment 11-24 is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for research applications. Certificates of Analysis (COA) detailing purity by HPLC, peptide content, and related substance profiles are available for each lot. Our quality commitment supports reproducible and reliable scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content (UV)	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.