Description

2-Hydroxydopamine is a synthetic neurotoxic compound structurally related to the neurotransmitter dopamine. It is a critical research chemical used extensively in neuroscience to selectively destroy catecholaminergic neurons, enabling the study of neurodegenerative processes. This compound is essential for researchers and pharmaceutical developers in the fields of neuropharmacology, neurodegenerative disease modeling, and neurotoxicity studies.

Application

• Neuroscience Research: Primary tool for creating experimental models of Parkinson's disease and other dopaminergic system disorders.
• Neurotoxicity Studies: Used to investigate mechanisms of selective neuronal death and evaluate potential neuroprotective agents.
• Pharmacological Screening: Serves as a benchmark compound in assays designed to discover new therapeutics for neurodegenerative conditions.
• Biochemical Pathway Analysis: Employed to study catecholamine metabolism, uptake, and oxidative stress pathways in neuronal cells.
• Academic & Institutional Research: Fundamental reagent in university and research institute laboratories for graduate and post-doctoral studies.
• Pharmaceutical R&D: Used in preclinical development stages to understand drug effects on compromised neuronal systems.

Basic Information

Item	Details
Product Name	2-Hydroxydopamine
CAS No.	4228-71-1
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	6-Hydroxydopamine; 2,4,5-Trihydroxyphenethylamine; 6-OHDA; 6-Hydroxy dopamine; Oxidopamine; 2,5,6-Trihydroxy-2-phenylethylamine; 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline (precursor form); NSC 36935
EINECS	224-193-9

Quality Control

Our 2-Hydroxydopamine is produced under stringent quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity and identity confirmation to ensure it meets the exacting standards required for sensitive biomedical research. A Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures will lead to decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.