Description

Iodomethane-13C is a stable isotope-labeled compound where the carbon atom is the carbon-13 (13C) isotope. This product, CAS NO 4227-95-6, is essential as an internal standard and tracer in advanced analytical chemistry and metabolic research, providing unparalleled accuracy for quantitative analysis. It is primarily required by research institutions, pharmaceutical developers, and analytical laboratories engaged in mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and environmental fate studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used for precise quantification in GC-MS and LC-MS methods, correcting for instrument variability and sample preparation losses.
• Metabolic Pathway Tracer: Enables the tracking and elucidation of biochemical pathways in pharmaceutical and agricultural chemical research.
• NMR Spectroscopy: Serves as a valuable 13C-labeled starting material or reference standard for structural analysis and reaction mechanism studies.
• Environmental Analysis: Acts as a labeled standard for detecting and quantifying volatile iodinated compounds in environmental samples.
• Pharmaceutical R&D: Critical in drug metabolism and pharmacokinetics (DMPK) studies to understand the fate of drug candidates.
• Chemical Synthesis Intermediate: Used in the synthesis of more complex 13C-labeled compounds for research purposes.

Basic Information

Product Name	Iodomethane-13C
CAS No.	4227-95-6
Molecular Formula	13CH3I
Molecular Weight	142.93 g/mol
Synonyms	Methyl-13C iodide; (13C)Methyl iodide; 13C-Labeled iodomethane; Carbon-13 methyl iodide; Methyl iodide-13C; Halon 10001-13C; UN 2644 (labeled variant)
EINECS	224-190-8 (for unlabeled compound)

Quality Control

Our Iodomethane-13C is produced and handled under strict quality protocols to ensure isotopic and chemical purity for sensitive research applications. Each batch is analyzed via NMR, GC-MS, and IR spectroscopy to confirm identity, isotopic enrichment (typically >99 atom % 13C), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical assay, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, preferably at 2-8°C to minimize volatility and degradation. Due to its highly volatile and light-sensitive nature, containers should be kept upright and handled in a fume hood.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
13C Isotopic Enrichment	≥ 99 atom %
Assay (GC)	≥ 98.0% (chemical purity)
Density (at 20°C)	2.28 - 2.30 g/mL
Refractive Index (n20D)	1.530 - 1.534

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.