Description

3,5-Bis(Trifluoromethyl)Phenylmethylsulfone is a high-value organofluorine building block characterized by its sulfone and bis(trifluoromethyl)phenyl groups. This compound is essential for introducing lipophilicity, metabolic stability, and unique electronic properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis and organocatalysis, enabling novel synthetic transformations.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and electronic materials to modify thermal stability, solubility, and optical properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags to study biological processes and protein interactions.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Phenylmethylsulfone
CAS No.	4210-04-2
Molecular Formula	C10H6F6O2S
Molecular Weight	304.21 g/mol
Synonyms	Methyl 3,5-Bis(trifluoromethyl)phenyl sulfone; [3,5-Bis(trifluoromethyl)phenyl](methyl)sulfone; 1-Methylsulfonyl-3,5-bis(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)phenyl Methyl Sulfone; α,α,α,α',α',α'-Hexafluoro-3,5-xylyl Methyl Sulfone; 3,5-Bis(trifluoromethyl)benzenemethanesulfonic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Every batch of 3,5-Bis(Trifluoromethyl)Phenylmethylsulfone is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.