Description

4,4,4-Trifluoro-1-(Pyridin-2-Yl)Butane-1,3-Dione is a specialized fluorinated diketone derivative that serves as a versatile and high-value building block in advanced chemical synthesis. Its unique structure, featuring a trifluoromethyl group and a pyridine moiety, makes it a critical precursor for developing novel compounds with tailored properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science sectors, where it is used to introduce fluorinated motifs and heterocyclic systems into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated heterocycles to modulate bioavailability, metabolic stability, and receptor binding.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Ligand Synthesis in Catalysis: Serves as a precursor for creating β-diketone and pyridine-based ligands used in coordination chemistry and metal-catalyzed reactions.
• Advanced Material Development: Employed in the research of organic electronic materials, such as OLEDs or semiconductors, where fluorination can improve charge transport and stability.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and exploratory synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	4,4,4-Trifluoro-1-(Pyridin-2-Yl)Butane-1,3-Dione
CAS No.	4027-51-4
Molecular Formula	C9H6F3NO2
Molecular Weight	217.15 g/mol
Synonyms	2-Pyridinyl-4,4,4-trifluoro-1,3-butanedione; 4,4,4-Trifluoro-1-(2-pyridinyl)-1,3-butanedione; 1-(Pyridin-2-yl)-4,4,4-trifluorobutane-1,3-dione; 2-Pyridoyltrifluoroacetone; PTFA; 4,4,4-Trifluoro-1-(2-pyridyl)-1,3-butanedione; 1-(2-Pyridinyl)-4,4,4-trifluoro-1,3-butanedione
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-1-(Pyridin-2-Yl)Butane-1,3-Dione is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to exclude moisture and returned to storage immediately after use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.