Description

2-Phenyl-Ethanesulfonyl Chloride is a versatile and reactive organosulfur compound, primarily used as a key sulfonylation reagent in organic synthesis. Its value lies in its ability to introduce the phenyl-ethanesulfonyl group, a crucial building block for creating sulfonamides and other functionalized molecules with specific properties. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the sulfonyl moiety enhances biological activity.
• Polymer Chemistry: Serves as a monomer or modifying agent for creating specialty polymers with tailored surface properties or reactivity.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals or organic semiconductors.
• Chemical Biology Probes: Utilized to synthesize activity-based probes for studying enzyme function and protein labeling.
• Custom Synthesis & Contract Manufacturing: A key reagent for fine chemical manufacturers offering bespoke synthesis services to clients.

Basic Information

Product Name	2-Phenyl-Ethanesulfonyl Chloride
CAS No.	4025-71-2
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	Phenethylsulfonyl chloride; (2-Phenylethyl)sulfonyl chloride; 2-Phenylethanesulfonyl chloride; β-Phenylethanesulfonyl chloride; Benzeneeethanesulfonyl chloride; PESC; EINECS 223-700-5
EINECS	223-700-5

Quality Control

Every batch of our 2-Phenyl-Ethanesulfonyl Chloride is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.