Description

3-(Chlorosulfonyl)Benzoic Acid is a versatile and reactive aromatic sulfonyl chloride derivative used as a key synthetic intermediate. Its bifunctional nature, featuring both a reactive sulfonyl chloride group and a carboxylic acid, makes it valuable for constructing complex molecules and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce sulfonamide or sulfonate functionalities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfonamide groups, which are common in diuretics, antibiotics, and protease inhibitors.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the sulfonyl moiety can enhance biological activity and selectivity.
• Dyestuff and Pigment Manufacturing: Serves as a precursor for sulfonated dyes and pigments, improving their solubility and affinity for various substrates.
• Polymer Modification: Employed to introduce sulfonyl chloride groups into polymer chains for subsequent cross-linking or to create ion-exchange resins and functional membranes.
• Chemical Research & Development: A valuable reagent in organic synthesis for constructing sulfonamides, sulfonate esters, and other derivatives in medicinal and materials chemistry.

Basic Information

Product Name	3-(Chlorosulfonyl)Benzoic Acid
CAS No.	4025-64-3
Molecular Formula	C7H5ClO4S
Molecular Weight	220.63 g/mol
Synonyms	3-Carboxybenzenesulfonyl chloride; Benzoic acid, 3-(chlorosulfonyl)-; m-(Chlorosulfonyl)benzoic acid; 3-Chlorosulfonylbenzoic acid; meta-Carboxybenzenesulfonyl chloride; NSC 403119; 3-Sulfobenzoic acid chloride
EINECS	223-700-4

Quality Control

Our 3-(Chlorosulfonyl)Benzoic Acid is manufactured under a strict quality management system. Each batch is analyzed to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.