Description

2-Fluorobenzotrichloride is a versatile and high-purity halogenated aromatic intermediate essential for advanced organic synthesis. Its core value lies in the reactive trichloromethyl group, which serves as a key building block for introducing the 2-fluorophenyl moiety into more complex molecular architectures. This compound is critically needed by R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential antiviral and anticancer agents.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides that benefit from the metabolic stability imparted by the fluorine atom.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated aromatic cores for advanced electronic display and lighting materials.
• Polymer Modification: Serves as a monomer or grafting agent for creating specialty polymers with enhanced chemical resistance or specific optical properties.
• Dye & Pigment Manufacturing: Intermediate for synthesizing fluorinated dyes and pigments that offer improved lightfastness and color properties.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.

Basic Information

Product Name	2-Fluorobenzotrichloride
CAS No.	488-98-2
Molecular Formula	C7H4Cl3F
Molecular Weight	213.46 g/mol
Synonyms	α,α,α-Trichloro-2-fluorotoluene; 2-Fluoro-α,α,α-trichlorotoluene; 2-Fluorophenyltrichloromethane; (2-Fluorophenyl)trichloromethane; 2-Fluorobenzylidyne trichloride; o-Fluorobenzotrichloride; Benzene, 1-fluoro-2-(trichloromethyl)-; 2-FBTCl
EINECS	207-685-6

Quality Control

Our 2-Fluorobenzotrichloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. The container must be kept tightly sealed in a dry environment to minimize moisture absorption and hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.5%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Density (at 20°C)	1.48 - 1.52 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.