Description

Holomycin is a naturally occurring pyrrole antibiotic compound with significant biological activity. This product is valued for its potent inhibitory effects against a broad spectrum of Gram-positive and Gram-negative bacteria, making it a crucial intermediate in advanced research and development. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for antimicrobial studies, novel drug discovery, and as a biochemical tool.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel antibiotic agents and antimicrobial therapies.
• Biochemical Research: Used as a selective inhibitor in microbiological and enzymatic studies to investigate bacterial growth mechanisms and resistance pathways.
• Antimicrobial Agent Development: Acts as a reference standard and active component in the development of new formulations targeting drug-resistant bacterial strains.
• Life Science Reagent: Employed in academic and industrial laboratories for in-vitro assays to study structure-activity relationships (SAR) of pyrrole-based compounds.
• Veterinary Medicine Research: Investigated for potential applications in developing treatments for bacterial infections in animals.

Basic Information

Product Name	Holomycin
CAS No.	488-04-0
Molecular Formula	C7H5NO3S2
Molecular Weight	215.25 g/mol
Synonyms	NSC 10483; 4,5-Dihydro-5-hydroxy-4-(hydroxyimino)-2-methyl-3H-pyrrole-3-carbothioic Acid S-Methyl Ester; 3H-Pyrrole-3-carbothioic acid, 4,5-dihydro-5-hydroxy-4-(hydroxyimino)-2-methyl-, S-methyl ester; Pyrrolomycin B; Antibiotic M-188
EINECS	207-667-9

Quality Control

Our Holomycin is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.