Description

Estriol 3-Sulfate is a sulfated metabolite of the endogenous estrogen estriol. This compound is of significant value as a high-purity reference standard and a critical intermediate in pharmaceutical research and development. It is primarily utilized by research institutions and manufacturers in the life sciences sector for analytical method development, metabolic studies, and the synthesis of more complex biochemical probes.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, LC-MS) to ensure accurate quantification of estrogens and their metabolites in biological samples.
• Biochemical Research: Serves as a key intermediate or substrate in studies of estrogen metabolism, sulfotransferase enzyme activity, and hormone signaling pathways.
• Diagnostic Kit Development: Employed in the manufacturing and quality control of diagnostic assays and kits designed to measure hormone levels.
• Metabolite Standard: Essential for conducting pharmacokinetic and bioequivalence studies to understand the disposition of estrogen-based therapeutics.

Basic Information

Product Name	Estriol 3-Sulfate
CAS No.	481-95-8
Molecular Formula	C18H22O6S
Molecular Weight	366.43 g/mol
Synonyms	Estriol 3-Sulfate; Estriol 3-Sulphate; E3S; 16α-Hydroxyestrone 3-sulfate; 1,3,5(10)-Estratriene-3,16α,17β-triol 3-sulfate; 3-Sulfooxyestra-1,3,5(10)-triene-16α,17β-diol; NSC 49110
EINECS	207-581-8

Quality Control

Our Estriol 3-Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods and purity determination by HPLC, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.