Description

2',4',6'-Trihydroxyacetophenone Monohydrate is a polyphenolic compound belonging to the acetophenone class, known for its specific substitution pattern. This chemical serves as a valuable building block and intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical and fine chemical sectors. It is primarily sought after by research institutions, pharmaceutical developers, and specialty chemical manufacturers for its role in creating compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of active pharmaceutical ingredients (APIs), especially those with antioxidant or anti-inflammatory properties.
• Fine Chemical Synthesis: Used as a precursor for creating complex organic molecules, including flavonoids and other polyphenolic derivatives in research and development.
• Biochemical Research: Employed in life science research as a standard or reagent to study enzyme inhibition, antioxidant mechanisms, and cellular pathways.
• Cosmetic Ingredient Intermediate: Potential use in the development of skincare actives where polyphenolic compounds are valued for their antioxidant benefits.
• Agrochemical Research: Investigated as an intermediate for developing novel plant protection agents or growth regulators.

Basic Information

Product Name	2',4',6'-Trihydroxyacetophenone Monohydrate
CAS No.	480-66-0
Molecular Formula	C8H8O4 • H2O
Molecular Weight	186.16 g/mol (Anhydrous basis: 168.15)
Synonyms	1-(2,4,6-Trihydroxyphenyl)ethanone Monohydrate; 2',4',6'-Trihydroxyacetophenone Hydrate; Phloroacetophenone Monohydrate; 2-Acetyl-1,3,5-trihydroxybenzene Monohydrate; 1-Acetyl-2,4,6-trihydroxybenzene Monohydrate; THAP Monohydrate
EINECS	207-560-1

Quality Control

Our 2',4',6'-Trihydroxyacetophenone Monohydrate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes results from HPLC, IR, and other relevant tests. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical research and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture. Recommended storage temperature is between 15°C and 25°C.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	8.0% - 10.0% (Theoretical for monohydrate: ~9.68%)
Loss on Drying	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.