Description

(4As)-3,4,4A,9,10,10Aα-Hexahydro-6-Hydroxy-1,1,4A-Trimethyl-7-Isopropylphenanthren-2(1H)-One is a complex, high-purity synthetic intermediate of significant interest in advanced organic synthesis. Its intricate steroidal-like phenanthrene core structure makes it a valuable building block for the development of novel chemical entities. This compound is primarily sought after by research institutions and pharmaceutical development laboratories for use in medicinal chemistry and as a precursor for specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly those targeting steroid hormone pathways.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and the synthesis of compound libraries for biological screening.
• Advanced Organic Synthesis: Acts as a critical starting material or intermediate in multi-step syntheses requiring complex, polycyclic frameworks with specific stereochemistry.
• Fine Chemical Production: Employed in the manufacture of high-value, low-volume specialty chemicals for research and niche industrial applications.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in related chemical processes.

Basic Information

Product Name	(4As)-3,4,4A,9,10,10Aα-Hexahydro-6-Hydroxy-1,1,4A-Trimethyl-7-Isopropylphenanthren-2(1H)-One
CAS No.	472-37-7
Molecular Formula	C20H30O2
Molecular Weight	302.45 g/mol
Synonyms	6-Hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthren-2-one; 7-Isopropyl-1,1,4a-trimethyl-1,2,3,4,4a,9,10,10a-octahydro-6H-phenanthren-2,6-diol; Aromadendrane-2,6-diol; NSC 403714; (4aR)-3,4,4a,9,10,10a-Hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-2(1H)-phenanthrenone
EINECS	Contact for details

Quality Control

Our (4As)-3,4,4A,9,10,10Aα-Hexahydro-6-Hydroxy-1,1,4A-Trimethyl-7-Isopropylphenanthren-2(1H)-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.