Description

Arenobufagin CAS NO 464-74-4 is a bioactive cardiotonic steroid belonging to the bufadienolide class, derived from natural sources. This compound is of significant interest for its specific biological activity and serves as a critical reference standard and research material. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and analytical laboratories engaged in cardiovascular studies, toxicology, and natural product chemistry.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the quality control and assay development of related pharmaceutical products and traditional medicines.
• Biomedical Research: Serves as a key biochemical tool for investigating Na+/K+-ATPase inhibition, cardiac glycoside activity, and related cell signaling pathways in cardiovascular and cancer research.
• Natural Product Isolation & Analysis: Acts as a critical marker compound for the identification, authentication, and standardization of botanical extracts and traditional remedies containing bufadienolides.
• Toxicology Studies: Employed in studies to understand the mechanisms of action, pharmacokinetics, and safety profiles of cardiotonic steroids.
• Academic & Institutional Research: Used in university and institutional labs for teaching and advanced research in medicinal chemistry and pharmacology.

Basic Information

Product Name	Arenobufagin
CAS No.	464-74-4
Molecular Formula	C₂₄H₃₂O₅
Molecular Weight	400.51 g/mol
Synonyms	3β,14-Dihydroxy-5β-bufa-20,22-dienolide; 3β,14-Dihydroxybufa-20,22-dienolide; Bufarenogin; Arenobufogenin; 14-Hydroxy-3-oxo-5β-bufa-20,22-dienolide (tautomer); NSC 529071
EINECS	Contact for details

Quality Control

Every batch of Arenobufagin is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results from multiple orthogonal analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.