Description

2-Fluoroethyl Chloroformate is a specialized fluorinated chloroformate ester, a key reagent in advanced organic synthesis. Its primary value lies in its role as a versatile building block for introducing the 2-fluoroethoxy moiety, a critical functional group in medicinal chemistry and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A crucial reagent for synthesizing fluorinated drug candidates, including potential antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced fluorinated pesticides and herbicides to enhance biological activity and stability.
• Peptide Chemistry: Acts as a protecting group or coupling agent in the synthesis of modified peptides.
• Polymer Modification: Serves as a monomer or modifier for creating fluorinated polymers with unique surface properties.
• Radiopharmaceuticals: Employed in the synthesis of fluorinated precursors for Positron Emission Tomography (PET) tracers.
• Liquid Crystal & OLED Materials: Used in the development of fluorinated organic electronic materials.

Basic Information

Product Name	2-Fluoroethyl Chloroformate
CAS No.	462-27-1
Molecular Formula	C3H4ClFO2
Molecular Weight	126.51 g/mol
Synonyms	2-Fluoroethyl carbonochloridate; Chloroformic acid 2-fluoroethyl ester; Ethanol, 2-fluoro-, 1-chloroformate; 2-Fluoroethanol chloroformate; Fluoroethyl chloroformate; 2-Fluoroethyl chlorocarbonate; 2-Fluoroethoxycarbonyl chloride
EINECS	207-320-7

Quality Control

Our 2-Fluoroethyl Chloroformate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acidity (Titration)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.