Description

Dihydrolipoic Acid CAS NO 462-20-4 is the reduced form of α-lipoic acid, a potent, naturally occurring antioxidant and essential cofactor for mitochondrial dehydrogenase enzymes. This compound matters for its superior ability to regenerate other antioxidants like vitamins C and E and directly neutralize a wide spectrum of free radicals. It is a critical ingredient for manufacturers in the pharmaceutical, nutraceutical, and advanced cosmetic industries seeking to develop high-efficacy antioxidant formulations.

Application

• Pharmaceutical Intermediates: Key building block for synthesizing advanced therapeutic agents targeting oxidative stress-related conditions.
• Dietary Supplements & Nutraceuticals: Core active ingredient in antioxidant, metabolic support, and anti-aging supplement formulations.
• Cosmetic & Skincare Actives: Used in anti-aging serums, creams, and lotions for its potent free radical scavenging and skin-brightening properties.
• Biochemical Research: Essential reagent in studies of mitochondrial function, redox biology, and cellular energy metabolism.
• Cell Culture Media & Additives: Employed as an antioxidant component in specialized cell culture systems to reduce oxidative damage.
• Veterinary Pharmaceuticals: Incorporated into antioxidant and hepatoprotective formulations for animal health.

Basic Information

Product Name	Dihydrolipoic Acid
CAS No.	462-20-4
Molecular Formula	C8H16O2S2
Molecular Weight	208.34 g/mol
Synonyms	DHLA; (R)-Dihydrolipoic Acid; 6,8-Dimercaptooctanoic Acid; Reduced Lipoic Acid; 1,2-Dithiolane-3-pentanoic Acid, Dihydro-; (+)-Dihydrolipoate; 6,8-Bis(sulfanyl)octanoic Acid; Thioctic Acid, Reduced
EINECS	207-334-8

Quality Control

Our Dihydrolipoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting specifications suitable for pharmaceutical and nutraceutical applications. Certificates of Analysis (COA) documenting key parameters such as assay, enantiomeric purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and light, minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (R)-enantiomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.