Description

2-Fluoro-4-Methylpyridine is a versatile fluorinated heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom and the pyridine nitrogen, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of novel organic electronic materials, liquid crystals, and functional polymers.
• Fluorine Chemistry Building Block: Utilized in nucleophilic aromatic substitution and cross-coupling reactions to introduce the 2-fluoro-4-methylpyridyl moiety into complex molecules.

Basic Information

Product Name	2-Fluoro-4-Methylpyridine
CAS No.	461-87-0
Molecular Formula	C6H6FN
Molecular Weight	111.12 g/mol
Synonyms	4-Methyl-2-fluoropyridine; 2-Fluoro-4-picoline; 2-Fluoro-γ-picoline; 2-Fluoro-4-methylpyridine; 4-Methyl-2-fluoro-pyridine; 2-Fluor-4-methylpyridin; Pyridine, 2-fluoro-4-methyl-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methylpyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its properties as a fluoride/strong alkali and highly volatile compound, ensure containers are kept tightly sealed and away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.