Description

1-Ethyl-4-Fluorobenzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an ethyl group and a fluorine atom on the benzene ring, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to introduce fluorine for enhanced bioactivity, stability, or specific electronic characteristics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the fluorophenyl moiety to modulate drug metabolism, bioavailability, and receptor binding.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom improves lipophilicity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to desired electronic properties and thermal stability.
• Polymer & Resin Modifier: Employed to synthesize fluorinated monomers or additives that enhance the chemical resistance, durability, and surface properties of high-performance polymers.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and as a starting material for further functionalization in medicinal and materials chemistry research.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring new fluorination methodologies and the effects of fluorine substitution.

Basic Information

Product Name	1-Ethyl-4-Fluorobenzene
CAS No.	459-47-2
Molecular Formula	C8H9F
Molecular Weight	124.16 g/mol
Synonyms	4-Ethylfluorobenzene; p-Ethylfluorobenzene; 1-Fluoro-4-ethylbenzene; 4-Fluoroethylbenzene; p-Fluoroethylbenzene; Ethyl-4-fluorobenzene; (4-Fluorophenyl)ethane
EINECS	Contact for details

Quality Control

Our 1-Ethyl-4-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to prevent evaporation and moisture absorption.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%
Density (20°C)	0.990 - 1.010 g/mL
Refractive Index (20°C)	1.480 - 1.490

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.