Description

2-Fluoro-5-Nitrotoluene is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its value lies in the strategic combination of a fluorine atom and a nitro group on a toluene backbone, enabling precise chemical modifications. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it serves as a key building block for active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing specialized fluorinated dyes and colorants.
• Liquid Crystal & Electronic Materials: Employed in the production of fluorinated components for liquid crystal displays (LCDs) and other electronic applications.
• Organic Synthesis & Research: A valuable reagent for academic and industrial research in cross-coupling reactions, nucleophilic aromatic substitution, and other fluorochemistry studies.
• Polymer Modification: Used to introduce fluorine-containing side chains into polymers to alter their physical and chemical properties.

Basic Information

Product Name	2-Fluoro-5-Nitrotoluene
CAS No.	455-88-9
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	1-Fluoro-2-methyl-4-nitrobenzene; 2-Methyl-4-nitrofluorobenzene; 5-Nitro-2-fluorotoluene; 4-Nitro-2-fluorotoluene; 2-Fluor-5-nitrotoluol; Toluene, 2-fluoro-5-nitro-; α-Fluoro-α-methyl-4-nitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitrotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	30-34 °C
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.