Description

4-(Fluorosulfonyl)Benzoic Acid is a versatile aromatic building block featuring both a reactive fluorosulfonyl group and a carboxylic acid moiety. This unique bifunctional structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce sulfonyl fluoride or benzoic acid derivatives into their molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs and other bioactive molecules targeting various disease pathways.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Probe Development: Serves as a starting material for synthesizing covalent inhibitors and activity-based probes (ABPs) in chemical biology and proteomics research.
• Polymer & Material Science: Employed to modify polymer backbones or create specialty monomers for high-performance resins and functional materials.
• Ligand & Catalyst Design: Useful for constructing complex ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Sulfonyl Fluoride Chemistry: The fluorosulfonyl group is a prime candidate for SuFEx (Sulfur Fluoride Exchange) click chemistry, enabling rapid, modular compound library generation.

Basic Information

Product Name	4-(Fluorosulfonyl)Benzoic Acid
CAS No.	455-26-5
Molecular Formula	C7H5FO4S
Molecular Weight	204.17 g/mol
Synonyms	4-Fluorosulfonylbenzoic Acid; p-(Fluorosulfonyl)benzoic Acid; Benzoic acid, 4-(fluorosulfonyl)-; 4-Carboxybenzenesulfonyl fluoride; p-Carboxybenzenesulfonyl fluoride; 4-FSO2-Benzoic Acid
EINECS	Contact for details

Quality Control

Our 4-(Fluorosulfonyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.