Description

3-Bromo-4-Chlorobenzotrifluoride is a versatile halogenated aromatic building block prized for its unique trifluoromethyl and halogen substituents, which impart significant electronic and steric properties. This compound is essential for facilitating complex molecular transformations in advanced synthetic chemistry. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the benzotrifluoride moiety.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where the halogenated aromatic core contributes to biological activity.
• Material Science: Serves as a precursor for liquid crystals, organic semiconductors, and other functional materials requiring specific fluorine-containing aromatic units.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and metal-halogen exchange reactions to construct diverse chemical libraries.
• Chemical Research: Utilized in academic and industrial R&D for exploring new reaction methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	3-Bromo-4-Chlorobenzotrifluoride
CAS No.	454-78-4
Molecular Formula	C7H3BrClF3
Molecular Weight	259.45 g/mol
Synonyms	1-Bromo-2-chloro-5-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluoro-5-bromotoluene; 3-Bromo-4-chloro-α,α,α-trifluorotoluene; 4-Chloro-3-bromobenzotrifluoride; 5-Bromo-4-chlorobenzotrifluoride; 3-Bromo-4-chloro-(trifluoromethyl)benzene; BTB; BCTF
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chlorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.