Description

Methyl Fluoroacetate CAS NO 453-18-9 is a highly volatile organic ester and a key fluorinated building block in advanced chemical synthesis. Its primary value lies in its ability to introduce the fluoroacetate moiety, a critical functional group for creating compounds with tailored biological and physical properties. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop novel active ingredients and sophisticated intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and diagnostic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and plant growth regulators that require a fluoroacetate functional group.
• Chemical Research & Development: A versatile building block in organic synthesis for creating novel fluorinated compounds in academic and industrial R&D labs.
• Specialty Chemical Manufacturing: Employed in the production of fluorinated surfactants, polymers, and liquid crystals.
• Biochemical Tool: Used in metabolic studies and as a probe in biochemical research due to its specific biological activity.

Basic Information

Product Name	Methyl Fluoroacetate
CAS No.	453-18-9
Molecular Formula	C3H5FO2
Molecular Weight	92.07 g/mol
Synonyms	Fluoroacetic Acid Methyl Ester; Methyl Fluoroethanoate; Methyl Monofluoroacetate; Methyl 2-Fluoroacetate; Methyl Ester of Fluoroacetic Acid; MFA; Methyl Ester of Monofluoroacetic Acid; 2-Fluoroacetic Acid Methyl Ester
EINECS	207-222-7

Quality Control

Our Methyl Fluoroacetate is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed and upright to prevent leakage and vapor accumulation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total
Density (20°C)	1.15 - 1.18 g/mL
Refractive Index (20°C)	1.365 - 1.375

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.