Description

4-Bromo-3-Fluorotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents on a toluene backbone, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Key pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Essential building block for agrochemical research, used in creating novel herbicides, fungicides, and insecticides.
• Precursor in material science for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Versatile reagent in organic synthesis for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution.
• Used in chemical research to study structure-activity relationships (SAR) and to introduce fluorine and bromine motifs into target molecules.
• Intermediate for the production of dyes and pigments with specific light-fastness and color properties.

Basic Information

Product Name	4-Bromo-3-Fluorotoluene
CAS No.	452-74-4
Molecular Formula	C7H6BrF
Molecular Weight	189.03 g/mol
Synonyms	1-Bromo-2-fluoro-4-methylbenzene; 2-Fluoro-4-methylbromobenzene; 3-Fluoro-4-bromotoluene; 4-Methyl-2-fluorobromobenzene; Toluene, 4-bromo-3-fluoro-; 4-Bromo-3-fluoro-1-methylbenzene; 2-Fluoro-4-bromotoluene
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.