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1,3-Dimethyl-4-Fluorobenzene CAS NO 452-65-3


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CAS No.:452-65-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,3-Dimethyl-4-Fluorobenzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both methyl and fluorine substituents, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

  • Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated benzene core.
  • Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and stability.
  • Liquid Crystal & OLED Materials: Serves as a fundamental building block for fluorine-containing compounds used in electronic display technologies.
  • Polymer & Resin Modifiers: Incorporated into specialty polymers to alter physical properties such as chemical resistance, thermal stability, and solubility.
  • Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a ligand precursor in catalytic systems.
  • Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing novel fluorinated dyes and pigments with unique color fastness and properties.

Basic Information

Item Details
Product Name 1,3-Dimethyl-4-Fluorobenzene
CAS No. 452-65-3
Molecular Formula C8H9F
Molecular Weight 124.16 g/mol
Synonyms 4-Fluoro-1,3-dimethylbenzene; 2,4-Dimethylfluorobenzene; 4-Fluoro-m-xylene; 1-Fluoro-2,4-dimethylbenzene; m-Xylene, 4-fluoro-; 2,4-Dimethyl-1-fluorobenzene; 4-Fluoro-2,4-dimethylbenzene; FDBM
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Quality Control

Our 1,3-Dimethyl-4-Fluorobenzene is produced under a stringent quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item Specification
Appearance Clear, colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 98.0%
Water Content (KF) ≤ 0.1%
Related Substances (GC) Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Density (20°C) 0.98 - 1.00 g/mL
Refractive Index (20°C) 1.485 - 1.495

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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