Description

1,2-Dimethyl-4-Fluorobenzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both methyl and fluorine substituents, makes it a key intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in research, development, and commercial-scale production.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes.
• Specialty Polymer Monomer: Employed in the production of high-performance polymers with specific thermal, chemical, or optical properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and creating novel fluorinated compounds.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where fluorine substitution alters color and fastness properties.

Basic Information

Product Name	1,2-Dimethyl-4-Fluorobenzene
CAS No.	452-64-2
Molecular Formula	C8H9F
Molecular Weight	124.16 g/mol
Synonyms	4-Fluoro-1,2-dimethylbenzene; 3,4-Dimethylfluorobenzene; 1-Fluoro-2,3-dimethylbenzene; 2,3-Dimethylfluorobenzene; 4-Fluoro-o-xylene; o-Xylene, 4-fluoro-; 2,3-Dimethyl-1-fluorobenzene; 452-64-2
EINECS	207-207-4

Quality Control

Our 1,2-Dimethyl-4-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Refractive Index (n20D)	1.485 - 1.495
Density (20°C)	1.00 - 1.05 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.