Description

Quinoline, 1,2,3,4-Tetrahydro-2-(Trifluoromethyl)- is a specialized heterocyclic organic compound featuring a quinoline core structure that is partially hydrogenated and substituted with a trifluoromethyl group. This unique molecular architecture makes it a valuable versatile building block and key intermediate in advanced chemical synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging the biological activity of the quinoline scaffold.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a core structure for developing electron-transport or host materials in electronic displays and lighting.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic processes, including asymmetric synthesis.
• Fluorinated Compound Research: The trifluoromethyl group makes it a valuable substrate for studying structure-activity relationships (SAR) in medicinal and materials chemistry.
• Fine Chemical and Specialty Chemical Production: Acts as a key intermediate for manufacturing dyes, pigments, and other high-value fluorinated compounds.

Basic Information

Item	Detail
Product Name	Quinoline, 1,2,3,4-Tetrahydro-2-(Trifluoromethyl)-
CAS No.	450-63-5
Molecular Formula	C11H10F3N
Molecular Weight	201.20 g/mol
Synonyms	2-(Trifluoromethyl)-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-2-(trifluoromethyl)quinoline; 2-Trifluoromethyl-1,2,3,4-tetrahydroquinoline; α,α,α-Trifluoro-1,2,3,4-tetrahydro-2-quinolinemethane; Tetrahydro-2-(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Our Quinoline, 1,2,3,4-Tetrahydro-2-(Trifluoromethyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.