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2-Fluoroethylbenzene CAS NO 446-49-1
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CAS No.:446-49-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Fluoroethylbenzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom, enabling precise molecular modifications that are difficult to achieve with other substituents. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it serves as a key intermediate for developing new active ingredients and functional materials.
Application
- Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and binding affinity.
- Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the introduction of fluorine can improve efficacy, environmental persistence, and selectivity.
- Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds, contributing to improved electronic properties and device performance.
- Organic Synthesis & Catalysis: Employed as a reagent in cross-coupling reactions and as a substrate for studying fluorine-specific reaction pathways in academic and industrial R&D.
- Fluorine-18 Radiochemistry: May be utilized as a precursor or model compound in the development of Positron Emission Tomography (PET) tracers for medical imaging.
Basic Information
| Product Name | 2-Fluoroethylbenzene |
| CAS No. | 446-49-1 |
| Molecular Formula | C8H9F |
| Molecular Weight | 124.16 g/mol |
| Synonyms | 1-Fluoro-2-ethylbenzene; (2-Fluoroethyl)benzene; o-Fluoroethylbenzene; 2-Ethylfluorobenzene; Benzene, (2-fluoroethyl)-; 446-49-1; 2-Fluoro-1-ethylbenzene; α-Fluoroethylbenzene |
| EINECS | 207-173-9 |
Quality Control
Our 2-Fluoroethylbenzene is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizing agents. Recommended storage temperature is 2-25°C. The container should be kept tightly sealed to prevent moisture absorption and volatilization.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear, colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Assay (GC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Related Substances (GC) | Individual impurity ≤ 1.0% |
| Density (20°C) | ~1.01 g/mL |
| Refractive Index (n20D) | ~1.495 |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.





