Description

3-Fluoro-4-Nitrotoluene is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a fluorine atom on the toluene backbone, makes it a critical building block for constructing complex molecules. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential antimicrobial and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides where the fluorine atom enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a starting material for producing specialized fluorinated dyes and colorants.
• Liquid Crystal & OLED Materials: An important building block for creating fluorinated components in electronic display and lighting technologies.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers to alter surface properties, chemical resistance, or thermal stability.
• Organic Synthesis Research: A valuable reagent for academic and industrial R&D exploring new fluorination reactions and coupling methodologies.

Basic Information

Product Name	3-Fluoro-4-Nitrotoluene
CAS No.	446-34-4
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	1-Fluoro-2-methyl-5-nitrobenzene; 2-Methyl-5-nitrofluorobenzene; 4-Nitro-3-fluorotoluene; 3-Fluoro-4-methylnitrobenzene; 5-Nitro-2-fluorotoluene; Toluene, 3-fluoro-4-nitro-; 2-Fluoro-5-nitrotoluene
EINECS	207-173-6

Quality Control

Our 3-Fluoro-4-Nitrotoluene is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for industrial chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48°C - 52°C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.