Description

2-Fluoronicotinic Acid Methyl Ester is a high-purity fluorinated pyridine derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for introducing the 2-fluoro-3-carbomethoxypyridine moiety into more complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of fluorinated drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic electronic materials and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing fluorinated analogs of bioactive molecules for mechanistic studies.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for bespoke chemical synthesis services.

Basic Information

Product Name	2-Fluoronicotinic Acid Methyl Ester
CAS No.	446-26-4
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	Methyl 2-fluoronicotinate; 2-Fluoropyridine-3-carboxylic acid methyl ester; 3-Carbomethoxy-2-fluoropyridine; Methyl 2-fluoro-3-pyridinecarboxylate; 2-Fluoro-3-methoxycarbonylpyridine; 2-Fluoro-3-pyridinecarboxylic acid methyl ester; 446-26-4; Methyl 2-fluoronicotinate
EINECS	Contact for details

Quality Control

Our 2-Fluoronicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.