Description

4-Fluoro-3-Nitrotoluene is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring both a nitro and a fluorine substituent on the toluene backbone, makes it a critical building block for the development of complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the fluorine atom enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a building block for synthesizing complex organic dyes and colorants.
• Liquid Crystal & Electronic Materials: Intermediate in the production of fluorinated compounds for electronic applications and display technologies.
• Organic Synthesis & Research: A valuable reagent for academic and industrial R&D in cross-coupling reactions and functional group transformations.
• Specialty Polymer Modification: Used to introduce fluorine and nitro functional groups into polymer chains to alter material properties.

Basic Information

Product Name	4-Fluoro-3-Nitrotoluene
CAS No.	446-11-7
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	1-Fluoro-2-methyl-5-nitrobenzene; 3-Nitro-4-fluorotoluene; 4-Fluoro-3-methylnitrobenzene; 2-Methyl-5-nitrofluorobenzene; 5-Nitro-2-fluorotoluene; 4-Fluoro-3-nitromethylbenzene; p-Fluoro-m-nitrotoluene; 446-11-7
EINECS	207-173-6

Quality Control

Our 4-Fluoro-3-Nitrotoluene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C/59-77°F). Due to its light-sensitive nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from heat, sparks, open flames, and incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	30 - 34 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.