Description

Benzenesulfonyl Fluoride, 5-Amino-2-Methyl- is a specialized aromatic sulfonyl fluoride derivative, distinguished by its reactive fluorine atom and aniline-like amino group. This compound is a critical building block in advanced organic synthesis, particularly valued for its role in creating sulfonamide-based structures. It is primarily utilized by pharmaceutical researchers and agrochemical developers for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel sulfonamide drugs, enzyme inhibitors, and targeted therapeutics.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Chemical Biology & Proteomics: Used as a reactive probe in activity-based protein profiling (ABPP) to study serine hydrolases and other enzymes.
• Material Science: Intermediate for creating specialized polymers, coatings, and functionalized surfaces with specific chemical properties.
• Cross-Coupling Reactions: Serves as an electrophilic coupling partner in palladium-catalyzed and other metal-mediated synthetic transformations.
• Fluorination Reagent: Source of the sulfonyl fluoride moiety for introducing fluorine into complex molecular architectures.

Basic Information

Product Name	Benzenesulfonyl Fluoride, 5-Amino-2-Methyl-
CAS No.	445-06-7
Molecular Formula	C7H8FNO2S
Molecular Weight	189.21 g/mol
Synonyms	5-Amino-2-methylbenzenesulfonyl fluoride; 2-Methyl-5-aminobenzenesulfonyl fluoride; 2-Methyl-5-aminophenylsulfonyl fluoride; 2-Methyl-5-aminobenzene-1-sulfonyl fluoride; 2-Methyl-5-aminophenyl sulfone fluoride; 5-Amino-o-toluenesulfonyl fluoride; 2-Methyl-5-nitrobenzenesulfonyl fluoride (precursor); 5-Amino-2-methylphenylsulfonyl fluoride
EINECS	Contact for details

Quality Control

Our production of Benzenesulfonyl Fluoride, 5-Amino-2-Methyl- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.