Description

5-Fluoro-2-Methylbenzenesulfonyl Chloride is a versatile and high-purity sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the sulfonyl functional group to create compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides requiring specific sulfonyl group chemistry.
• Material Science Research: Employed in the creation of specialty polymers and functional materials where sulfonyl groups modify physical properties.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing sulfonated dyes and colorants with enhanced solubility and fastness.
• Cross-coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions to construct complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	5-Fluoro-2-Methylbenzenesulfonyl Chloride
CAS No.	445-05-6
Molecular Formula	C7H6ClFO2S
Molecular Weight	208.64 g/mol
Synonyms	2-Methyl-5-fluorobenzenesulfonyl chloride; 5-Fluoro-o-toluenesulfonyl chloride; 1-Fluoro-4-methyl-3-sulfonylchloridobenzene; 2-Fluoro-5-methylbenzenesulfonyl chloride; 5-Fluoro-2-toluenesulfonyl chloride; 3-Fluoro-6-methylbenzenesulfonyl chloride; Benzenesulfonyl chloride, 5-fluoro-2-methyl-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.