Description

5-Bromo-2-Chlorobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring bromine, chlorine, and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated benzotrifluoride core.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific properties such as chemical resistance, thermal stability, or altered refractive index.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine substituent.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	5-Bromo-2-Chlorobenzotrifluoride
CAS No.	445-01-2
Molecular Formula	C7H3BrClF3
Molecular Weight	259.45 g/mol
Synonyms	2-Chloro-5-bromobenzotrifluoride; 1-Bromo-4-chloro-2-(trifluoromethyl)benzene; 5-Bromo-2-chloro-α,α,α-trifluorotoluene; 2-Chloro-α,α,α-trifluoro-5-bromotoluene; 5-Bromo-2-chloro-(trifluoromethyl)benzene; Benzenemethanol, 5-bromo-2-chloro-α,α,α-trifluoro-; (5-Bromo-2-chlorophenyl)trifluoromethane
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chlorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.