Description

Benzenesulfonyl Chloride, 4-Nitro-2-(Trifluoromethyl)- is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride group and electron-withdrawing nitro and trifluoromethyl substituents. This compound is essential for introducing the 4-nitro-2-(trifluoromethyl)benzenesulfonyl moiety into target molecules, enabling the synthesis of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that benefit from the stability imparted by the trifluoromethyl group.
• Dyestuff and Pigment Production: Serves as a precursor for synthesizing specialized azo dyes and organic pigments.
• Polymer Modification: Employed to introduce sulfonyl groups into polymer chains, altering properties like solubility and thermal stability.
• Chemical Research & Development: A versatile reagent in organic synthesis for constructing complex molecular architectures in academic and industrial R&D.
• Liquid Crystal and OLED Material Development: Used in the synthesis of electron-transport or emissive layer materials for electronic displays.

Basic Information

Product Name	Benzenesulfonyl Chloride, 4-Nitro-2-(Trifluoromethyl)-
CAS No.	444-46-2
Molecular Formula	C7H3ClF3NO4S
Molecular Weight	289.61 g/mol
Synonyms	4-Nitro-2-(trifluoromethyl)benzenesulfonyl chloride; 2-Trifluoromethyl-4-nitrobenzenesulfonyl chloride; 4-Nitro-alpha,alpha,α-trifluoro-o-toluenesulfonyl chloride; p-Nitro-o-trifluoromethylbenzenesulfonyl chloride; 1-(Chlorosulfonyl)-2-(trifluoromethyl)-4-nitrobenzene; NSC 403107; 4-Nitro-2-trifluoromethylbenzenesulfonyl chloride
EINECS	207-150-4

Quality Control

Our Benzenesulfonyl Chloride, 4-Nitro-2-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.