Description

3,5-Dibromo-4-Fluorotoluene is a halogenated aromatic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents on a toluene backbone, makes it an essential intermediate for creating complex molecules with tailored properties. This high-purity intermediate is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic motifs to modulate bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the dibromo-fluorotoluene structure contributes to product efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its ability to influence molecular polarity and mesomorphic properties.
• Polymer & Resin Modifier: Employed to introduce halogenated aromatic units into polymer chains, enhancing flame retardancy, thermal stability, and chemical resistance of high-performance plastics and coatings.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille), enabling the efficient construction of complex biaryl systems prevalent in modern organic chemistry.
• Chemical Research & Development: A valuable reagent for academic and industrial research labs exploring new synthetic methodologies and novel compound libraries.

Basic Information

Item	Details
Product Name	3,5-Dibromo-4-Fluorotoluene
CAS No.	444-13-3
Molecular Formula	C7H5Br2F
Molecular Weight	267.92 g/mol
Synonyms	4-Fluoro-3,5-dibromotoluene; 1,3-Dibromo-2-fluoro-5-methylbenzene; 2-Fluoro-3,5-dibromotoluene; Toluene, 3,5-dibromo-4-fluoro-; 3,5-Dibromo-4-fluoro-1-methylbenzene; 3,5-Dibromo-p-fluorotoluene; 4-Fluorotoluene-3,5-dibromide
EINECS	Contact for details

Quality Control

Our 3,5-Dibromo-4-Fluorotoluene is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all test results are provided and available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. Handle and store under an inert atmosphere if prolonged storage is required to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.