Description

2-Fluoro-6-Iodotoluene is a versatile fluorinated and iodinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both halogen substituents, makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine and iodine atoms contribute to biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or host materials for OLED devices.
• Cross-Coupling Reactions: The iodine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form biaryl systems.
• Fluorine Chemistry Research: A valuable substrate for studying nucleophilic aromatic substitution and other fluorochemical transformations.
• Material Science: Intermediate for creating specialized polymers and advanced organic materials with tailored electronic properties.

Basic Information

Product Name	2-Fluoro-6-Iodotoluene
CAS No.	443-85-6
Molecular Formula	C7H6FI
Molecular Weight	236.03 g/mol
Synonyms	1-Fluoro-2-iodo-3-methylbenzene; 2-Fluoro-6-methyl-1-iodobenzene; 3-Methyl-2-fluoro-1-iodobenzene; 2-Fluoro-6-methylphenyl iodide; 2-Iodo-6-fluorotoluene; o-Fluoro-m-iodotoluene; 443-85-6; 2-Fluoro-6-iodotoluene
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-Iodotoluene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.