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2,6-Difluorotoluene CAS NO 443-84-5


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CAS No.:443-84-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,6-Difluorotoluene is a versatile fluorinated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and specialty chemicals.

Application

  • Pharmaceutical Intermediate: Key starting material for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs.
  • Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and stability.
  • Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic displays and organic light-emitting diodes.
  • Polymer & Resin Modifier: Incorporated to impart specific characteristics like chemical resistance or altered solubility in high-performance polymers.
  • Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to introduce the difluorotoluene moiety.
  • Research & Development: Utilized in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name 2,6-Difluorotoluene
CAS No. 443-84-5
Molecular Formula C7H6F2
Molecular Weight 128.12 g/mol
Synonyms 1,3-Difluoro-2-methylbenzene; 2-Methyl-1,3-difluorobenzene; 2,6-Difluoromethylbenzene; α,α,2,6-Tetrafluorotoluene (incorrect but common misnomer); 2,6-DFT; Difluorotoluene (mixed isomer); Benzene, 1,3-difluoro-2-methyl-; Toluene, 2,6-difluoro-
EINECS 207-143-5

Quality Control

Our 2,6-Difluorotoluene is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 98.0%
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.1%
Related Substances (GC) Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Density (at 20°C) 1.15 - 1.18 g/mL
Boiling Point Approx. 140-142 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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