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2,6-Difluorotoluene CAS NO 443-84-5
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CAS No.:443-84-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2,6-Difluorotoluene is a versatile fluorinated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and specialty chemicals.
Application
- Pharmaceutical Intermediate: Key starting material for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs.
- Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and stability.
- Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic displays and organic light-emitting diodes.
- Polymer & Resin Modifier: Incorporated to impart specific characteristics like chemical resistance or altered solubility in high-performance polymers.
- Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to introduce the difluorotoluene moiety.
- Research & Development: Utilized in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.
Basic Information
| Product Name | 2,6-Difluorotoluene |
| CAS No. | 443-84-5 |
| Molecular Formula | C7H6F2 |
| Molecular Weight | 128.12 g/mol |
| Synonyms | 1,3-Difluoro-2-methylbenzene; 2-Methyl-1,3-difluorobenzene; 2,6-Difluoromethylbenzene; α,α,2,6-Tetrafluorotoluene (incorrect but common misnomer); 2,6-DFT; Difluorotoluene (mixed isomer); Benzene, 1,3-difluoro-2-methyl-; Toluene, 2,6-difluoro- |
| EINECS | 207-143-5 |
Quality Control
Our 2,6-Difluorotoluene is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow clear liquid |
| Identification (IR) | Conforms to structure |
| Assay (GC) | ≥ 98.0% |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.1% |
| Related Substances (GC) | Individual impurity ≤ 0.5%, Total impurities ≤ 2.0% |
| Density (at 20°C) | 1.15 - 1.18 g/mL |
| Boiling Point | Approx. 140-142 °C |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.





