Description

2-Chloro-6-Fluorotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents on the toluene ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the chloro-fluoro substitution pattern enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating halogenated aromatic cores in electronic materials for displays and lighting.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitution reactions due to its reactive halogen sites.
• Dye & Pigment Intermediate: Used in the manufacture of specialized halogenated dyes and pigments.
• Polymer Modification: Acts as a monomer or functionalizing agent for engineering plastics and high-performance polymers.

Basic Information

Product Name	2-Chloro-6-Fluorotoluene
CAS No.	443-83-4
Molecular Formula	C7H6ClF
Molecular Weight	144.57 g/mol
Synonyms	1-Chloro-2-fluoro-3-methylbenzene; 2-Fluoro-6-chlorotoluene; 3-Methyl-2-fluoro-1-chlorobenzene; o-Chloro-m-fluorotoluene; 2-Chloro-6-fluoromethylbenzene; 2-Fluoro-6-chloromethylbenzene; Benzene, 1-chloro-2-fluoro-3-methyl-
EINECS	207-145-8

Quality Control

Our 2-Chloro-6-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global clientele in research and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.2%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	1.20 - 1.25 g/mL
Refractive Index (n20D)	1.495 - 1.505

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.