Description

3-Fluoro-o-Xylene is a versatile fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring a fluorine atom adjacent to two methyl groups on a benzene ring, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) agents and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials, improving charge transport and thermal stability.
• Polymer Modification: Incorporated into specialty polymers and resins to impart specific chemical resistance, lower dielectric constants, or modify surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a starting material for synthesizing complex fluorinated aromatic compounds in R&D laboratories.
• Dye & Pigment Industry: Utilized in the production of fluorinated dyes and pigments that offer enhanced lightfastness and color properties.

Basic Information

Product Name	3-Fluoro-o-Xylene
CAS No.	443-82-3
Molecular Formula	C8H9F
Molecular Weight	124.16 g/mol
Synonyms	1,2-Dimethyl-3-fluorobenzene; 3-Fluoro-1,2-dimethylbenzene; o-Xylene, 3-fluoro-; 3-Fluoro-o-dimethylbenzene; 3-Fluorobenzene-1,2-dimethyl; 2,3-Dimethylfluorobenzene; 3-Fluoro-ortho-xylene
EINECS	207-146-7

Quality Control

Our 3-Fluoro-o-Xylene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR), to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent evaporation and minimize moisture absorption.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	1.00 - 1.02 g/mL
Refractive Index (n20D)	1.495 - 1.505

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.