Description

2-Fluoro-6-Methylpyridine is a versatile fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom at the 2-position, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluoropyridine moiety to modulate bioavailability, metabolic stability, or binding affinity.
• Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, where the fluorine atom enhances biological activity and environmental persistence profiles.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing character and structural rigidity.
• Chemical Biology Probes: Utilized as a building block for fluorinated analogs of biomolecules, aiding in metabolic pathway studies and drug discovery through isotopic or isosteric replacement.
• Fine Chemical Production: Acts as a versatile intermediate for the manufacture of various specialty and fine chemicals requiring selective fluorination.

Basic Information

Product Name	2-Fluoro-6-Methylpyridine
CAS No.	407-22-7
Molecular Formula	C6H6FN
Molecular Weight	111.12 g/mol
Synonyms	2-Fluoro-6-picoline; 6-Methyl-2-fluoropyridine; 2-Fluoro-6-methylpyridine; 2-Fluor-6-methylpyridin; 407-22-7; 2-Fluoro-6-methyl-pyridine; Pyridine, 2-fluoro-6-methyl-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Methylpyridine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and open flames. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.