Description

3-Bromo-5-Fluoropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the introduction of both bromine and fluorine substituents into complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of functionalized ligands for catalysis and as a monomer for specialty polymers.
• Cross-Coupling Reactions: Serves as an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Fluorine Chemistry Research: A valuable reagent for studying nucleophilic aromatic substitution and other fluorine-specific transformations in academic and industrial R&D.
• Liquid Crystal & OLED Materials: Used as a building block for electron-transport materials and other components in electronic displays.

Basic Information

Product Name	3-Bromo-5-Fluoropyridine
CAS No.	407-20-5
Molecular Formula	C5H3BrFN
Molecular Weight	175.99 g/mol
Synonyms	5-Fluoro-3-bromopyridine; 3-Bromo-5-fluoropyridine; 5-Bromo-3-fluoropyridine; 3-Bromo-5-fluoro-pyridine; Pyridine, 3-bromo-5-fluoro-; 407-20-5; 3-Br-5-F-Py; 3-Bromo-5-fluoro pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.