Description

1-Fluoro-4-Isopropylbenzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its structure, featuring both a fluorine atom and an isopropyl group on the benzene ring, makes it a key intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal & Electronic Materials: Acts as a building block for fluorinated liquid crystals and organic semiconductors, contributing to desired dielectric and optical properties.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a ligand precursor in organometallic chemistry due to its electron-withdrawing fluorine substituent.
• Flavor & Fragrance Industry: Can be utilized in the synthesis of complex aromatic compounds for specialty fragrances and flavors.
• Polymer Modification: Used to introduce fluorine-containing side chains into polymers to alter surface properties, such as hydrophobicity and chemical resistance.

Basic Information

Item	Detail
Product Name	1-Fluoro-4-Isopropylbenzene
CAS No.	403-39-4
Molecular Formula	C9H11F
Molecular Weight	138.18 g/mol
Synonyms	p-Fluoroisopropylbenzene; 4-Fluoro-1-isopropylbenzene; 4-Isopropylfluorobenzene; 1-Isopropyl-4-fluorobenzene; (4-Fluorophenyl)propane; 4-Fluorocumene; p-Isopropylfluorobenzene; FIPB
EINECS	206-953-8

Quality Control

Every batch of 1-Fluoro-4-Isopropylbenzene is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical testing is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing specific results for each parameter is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Refractive Index (20°C)	1.480 - 1.490
Density (20°C)	0.980 - 1.000 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.