Description

2-Fluoropyridine-6-Carboxylic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a fluorine substituent on the pyridine ring, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for metabolic and mechanistic studies.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated heterocyclic architectures.

Basic Information

Product Name	2-Fluoropyridine-6-Carboxylic Acid
CAS No.	402-69-7
Molecular Formula	C6H4FNO2
Molecular Weight	141.10 g/mol
Synonyms	6-Fluoropicolinic Acid; 2-Fluoro-6-pyridinecarboxylic Acid; 2-Fluoropyridine-6-carboxylic acid; 6-Fluoro-2-pyridinecarboxylic Acid; 2-Fluoro-6-picolinic Acid; 6-Fluoropyridine-2-carboxylic Acid; Picolinic acid, 6-fluoro-; 2-Fluoropicolinic Acid
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure the consistency and purity of our 2-Fluoropyridine-6-Carboxylic Acid. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to verify identity and purity against stringent in-house specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.