Description

4-Fluorobenzotrifluoride is a versatile fluorinated aromatic building block of significant industrial importance. Its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts valuable properties such as enhanced lipophilicity, metabolic stability, and chemical reactivity. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it serves as a key intermediate for synthesizing complex molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic motifs to modulate bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Employed to introduce fluorine-containing groups into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis: A valuable reagent in cross-coupling reactions and as a substrate for developing novel fluorination methodologies in academic and industrial R&D.
• Dye & Pigment Manufacturing: Used in the synthesis of specialized fluorinated dyes and pigments that offer superior lightfastness and color properties.

Basic Information

Product Name	4-Fluorobenzotrifluoride
CAS No.	402-44-8
Molecular Formula	C7H4F4
Molecular Weight	164.10 g/mol
Synonyms	1-Fluoro-4-(trifluoromethyl)benzene; α,α,α,4-Tetrafluorotoluene; p-(Trifluoromethyl)fluorobenzene; 4-(Trifluoromethyl)fluorobenzene; p-Fluorobenzotrifluoride; 4-Fluoro-α,α,α-trifluorotoluene; Benzene, 1-fluoro-4-(trifluoromethyl)-
EINECS	206-943-6

Quality Control

Our 4-Fluorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	1.30 - 1.35 g/mL
Refractive Index (n20D)	1.400 - 1.410

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.