Description

4-Bromobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the combination of a reactive bromine substituent and a stable, electron-withdrawing trifluoromethyl group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries who require high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the CF₃ group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed reactions like Suzuki, Heck, and Stille couplings to form complex biaryl structures.
• Functional Polymer Monomer: Incorporated into polymers to impart specific properties such as chemical resistance, thermal stability, or unique optical characteristics.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	4-Bromobenzotrifluoride
CAS No.	402-43-7
Molecular Formula	C₇H₄BrF₃
Molecular Weight	225.01 g/mol
Synonyms	1-Bromo-4-(trifluoromethyl)benzene; p-Bromobenzotrifluoride; α,α,α-Trifluoro-p-bromotoluene; 4-Bromo-α,α,α-trifluorotoluene; p-Bromo(trifluoromethyl)benzene; (4-Bromophenyl)trifluoromethane; 4-Bromo-α,α,α-trifluoromethylbenzene; 4-Bromobenzylidene trifluoride
EINECS	206-937-7

Quality Control

Our 4-Bromobenzotrifluoride is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency that meets the demanding requirements of fine chemical synthesis. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	1.60 - 1.65 g/mL
Refractive Index (n20/D)	1.460 - 1.470

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.