Description

3-Cyanobenzenesulfonyl Fluoride is a versatile aromatic sulfonyl fluoride derivative, serving as a key building block in advanced organic synthesis. Its reactive sulfonyl fluoride group makes it an essential precursor for the development of pharmaceuticals, agrochemicals, and functional materials. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and fine chemical industries seeking to incorporate the benzenesulfonyl moiety into complex molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Chemical Biology & Proteomics: Used as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with sulfonyl fluoride functionalities.
• Material Science: Employed in the production of specialty polymers, coatings, and advanced materials requiring specific surface modifications.
• Organic Synthesis Reagent: Utilized in Suzuki-Miyaura cross-coupling and other palladium-catalyzed reactions to introduce functionalized aryl groups.
• Fluorination Chemistry: Acts as a source of the sulfonyl fluoride group for synthesizing other fluorinated compounds.

Basic Information

Product Name	3-Cyanobenzenesulfonyl Fluoride
CAS No.	402-27-7
Molecular Formula	C7H4FNO2S
Molecular Weight	185.17 g/mol
Synonyms	3-Cyanobenzenesulfonyl fluoride; m-Cyanobenzenesulfonyl fluoride; 3-Cyano-benzenesulfonyl fluoride; Benzenesulfonyl fluoride, 3-cyano-; 3-(Fluorosulfonyl)benzonitrile; m-(Fluorosulfonyl)benzonitrile; 402-27-7; 3-CBSF
EINECS	Contact for details

Quality Control

Our 3-Cyanobenzenesulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.