Description

4-Bromo-3-Methoxybenzotrifluoride is a versatile halogenated aromatic building block characterized by its bromine and trifluoromethyl substituents. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. Industries that require high-purity, functionalized intermediates for coupling reactions and material science will find this product essential for their development pipelines.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethylated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromine atom serves as a handle for further functionalization.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials due to the electron-withdrawing properties of the trifluoromethyl group.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D for constructing diverse chemical libraries and exploring new reaction methodologies.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where halogen and methoxy groups influence color and fastness properties.

Basic Information

Item	Detail
Product Name	4-Bromo-3-Methoxybenzotrifluoride
CAS No.	402-07-3
Molecular Formula	C8H6BrF3O
Molecular Weight	255.04 g/mol
Synonyms	1-Bromo-2-Methoxy-4-(Trifluoromethyl)benzene; 4-Bromo-α,α,α-Trifluoro-3-Methoxytoluene; 2-Methoxy-4-(Trifluoromethyl)Bromobenzene; 3-Methoxy-4-Bromobenzotrifluoride; 4-Bromo-3-Methoxybenzotrifluoride; 4-Bromo-α,α,α-Trifluoro-m-Anisole; 4-Bromo-3-Methoxy-α,α,α-Trifluorotoluene; 4-Bromo-3-Methoxy-1-(Trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Methoxybenzotrifluoride is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.