Description

2-Bromo-5-Methoxybenzotrifluoride is a versatile halogenated aromatic building block characterized by its trifluoromethyl and methoxy substituents. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. Industries that require high-purity, functionalized aromatic compounds for active ingredient development are the primary users of this material.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), especially in molecules requiring a substituted benzotrifluoride core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty electronic chemicals for displays and organic light-emitting diodes.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a ligand precursor in organometallic chemistry.
• Dye & Pigment Manufacturing: Acts as an intermediate for creating specialized colorants and functional dyes.
• Material Science Research: Utilized in the development of novel polymers and advanced materials with specific electronic or surface properties.

Basic Information

Product Name	2-Bromo-5-Methoxybenzotrifluoride
CAS No.	400-72-6
Molecular Formula	C8H6BrF3O
Molecular Weight	255.04 g/mol
Synonyms	1-Bromo-4-methoxy-2-(trifluoromethyl)benzene; 4-Methoxy-2-(trifluoromethyl)bromobenzene; 2-Bromo-α,α,α-trifluoro-5-methoxytoluene; 5-Methoxy-2-bromobenzotrifluoride; 2-Bromo-5-methoxy-α,α,α-trifluorotoluene; 4-Methoxy-2-trifluoromethylbromobenzene; Benzene, 1-bromo-4-methoxy-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methoxybenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.