Description

2,4,5-Trimethylfluorobenzene CAS NO 400-01-1 is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring three methyl groups and a fluorine atom on the benzene ring, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for catalysis and asymmetric synthesis.
• Polymer & Resin Modifier: Incorporated into polymer chains to impart specific characteristics such as altered solubility, thermal stability, or chemical resistance.
• Chemical Research & Development: A valuable reagent for exploring novel fluorination chemistry and constructing complex molecular frameworks in academic and industrial labs.

Basic Information

Product Name	2,4,5-Trimethylfluorobenzene
CAS No.	400-01-1
Molecular Formula	C9H11F
Molecular Weight	138.18 g/mol
Synonyms	1-Fluoro-2,4,5-trimethylbenzene; Fluoromesitylene; 2,4,5-Trimethyl-1-fluorobenzene; 2,4,5-Trimethylphenyl fluoride; (2,4,5-Trimethylphenyl)fluoride; F-mesitylene; Mesityl fluoride
EINECS	206-897-1

Quality Control

Our 2,4,5-Trimethylfluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.