Description

4-Chlorobenzenesulfonyl Chloride is a versatile and highly reactive organosulfur compound, primarily used as a key sulfonating and sulfonylating agent in organic synthesis. Its value lies in its ability to introduce the 4-chlorobenzenesulfonyl functional group, a crucial building block for creating molecules with specific biological and material properties. This intermediate is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity raw materials for research and production.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of sulfonamide drugs, including diuretics, antibacterial agents, and COX-2 inhibitors.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the sulfonyl chloride group acts as a reactive handle.
• Dye and Pigment Manufacturing: Serves as an intermediate for creating sulfonated dyes and colorants with improved solubility and fastness properties.
• Polymer Modification: Employed to introduce sulfonyl groups into polymer chains, altering properties like hydrophilicity, adhesion, and thermal stability.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research to explore new chemical entities.
• Surfactant Production: Acts as a precursor for anionic surfactants used in various industrial and cleaning formulations.

Basic Information

Product Name	4-Chlorobenzenesulfonyl Chloride
CAS No.	48-60-2
Molecular Formula	C6H4Cl2O2S
Molecular Weight	211.06 g/mol
Synonyms	p-Chlorobenzenesulfonyl Chloride; 4-Chlorobenzene-1-sulfonyl Chloride; 1-Chloro-4-(chlorosulfonyl)benzene; Benzenesulfonyl Chloride, 4-chloro-; PCSC; 4-CBSC; 4-Chlorophenylsulfonyl Chloride; NSC 406916
EINECS	200-358-4

Quality Control

Our 4-Chlorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing assay, impurity profiles, and physical characteristics. Our quality commitment supports compliance with cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed to prevent decomposition from atmospheric moisture. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	50 - 54 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.